Endocrine Abstracts

Introduction: Klinefelter’s syndrome (KFS) is associated with an increased risk of certain malignancies; including leukemia, breast cancer and mediastinal germ cell tumours. Testicular tumours are uncommon. Epidermoid cysts are benign tumours of hair-growing areas. Testicular epidermoid cysts are very rare and account for 1–2% of all testicular tumours. We report a rare case of bilateral epidermoid cysts in a patient with Klinefelter’s syndrome.<p class="abs...

Introduction: Gastric bypass surgery is performed for intractable severe reflux oesophagitis not amenable to vagotomy and pyloroplasty. Long-term complications include dumping syndrome, nutritional deficiencies, incisional hernia and weight loss. We report a case of unexplained adrenal insufficiency in a patient who had gastric bypass surgery.Case: A 77-year-old gentleman presented with a history of recurrent hypoglycaemic episodes. Hypoglycaemic symptom...

Introduction: Glycated haemoglobin (HbA1c) is used to measure glycaemic control in patients with diabetes, and accuracy depends on normal erythrocyte lifespan. Dapsone causes spuriously low HbA1c results by reducing erythrocyte lifespan through haemolysis and methaemoglobin formation, which interferes with the liquid-chromatography method used to measure HbA1c. Dapsone-induced haemolysis (DIH) is mostly reported in patients with glucose-6-phosphate dehydrogenase (G6PD) deficie...